I think emerging research in genome engineering and sculpting evolutionary fitness using genome engineering tools will probably solve these disorders. However,

I think emerging research in genome engineering and sculpting evolutionary fitness using genome engineering tools will probably solve these disorders. However, these technologies have--in my opinion--lower hanging and more profitable fruit in other biomedical interventions, such as cancer therapy. They will probably cure mitochondrial disorders as a side-effect, though, and possibly by small start-ups (since there's such little money in these rare, one-shot-cure diseases). I'm a Ph.D. candidate in systems biology.