8 ms·

I've personally seen MDMA fix two marriages, with one session each. Its divine stuff. I'm very happy that new studies have been completed or are being planned

by cnp 13y ago

I've personally seen MDMA fix two marriages, with one session each. Its divine stuff. I'm very happy that new studies have been completed or are being planned to further explore the psychotherapeutical side of the drug. But aside from that, I agree. It's the best. No hangover (if it's pure), short duration, music sounds amazing, an amplified sense of intellectual focus and compassion, and good times with friends. You can't ask for anything more from an intoxicant. Its the best.

kittycow 13y ago
agreed. I take one whenever i go to a job interview. Without it I'm a stuttering idiot during an interview. where as with ecstasy I turn in to the dos equis beer guy.
- thathonkey 13y ago
  you probably feel like dos equis beer guy but to the interviewer you just have pupils the size of saucers and can't stop feeling the fabric of your clothes really earnestly
- CocaKoala 13y ago
  How often to you go to job interviews? If you have lots of them and take MDMA before each one, I think it might not be as helpful as you feel it is.
  - kittycow 13y ago
    good point!
WarDekar 13y ago
No hangover? Except for, let's see, a short list: Severely depleted serotonin levels, causing irritability and possibly depression Loss of focus, concentration, and attention (good luck programming competently the day after) Bruxism (jaw clenching/grinding)
- cnp 13y ago
  Hangovers tend to occur when you've had MDMA mixed with one of the ever-more-frequent mixers such as methamphetamine, cocaine or even MDA, which actually targets dopamine receptors far more prominently than the serotonin and knock you out for days. Pressed pills are usually the culprit, and I would avoid them unless you know exactly where they're coming from. From a wide array of experience, pure MDMA (in recommended doses, meaning 200mg or less) produces less of a hangover than two beers, with a very real "afterglow" which lasts for days after. Excellent focus and concentration included. This is a good read: http://www.cbc.ca/news/canada/british-columbia/pure-ecstasy-can-be-safe-for-adults-health-official-says-1.1229517 http://www.cbc.ca/news/canada/british-columbia/pure-ecstasy-...
  - WarDekar 13y ago
    From your own article: "The drug's letdown can include feelings of confusion, irritability, anxiety, paranoia and depression, and people may experience memory loss or sleep problems, jaundice or liver damage." And: "Dr. John Halpern, a Harvard Medical School assistant professor who led the research, said pure MDMA can change core body temperature, heart rate and blood pressure in the short-term, and decrease immune resistance for a few days." Sounds like a hangover to me: "2a : disagreeable physical effects following heavy consumption of alcohol or the use of drugs" http://www.merriam-webster.com/dictionary/hangover http://www.merriam-webster.com/dictionary/hangover I'm not saying MDMA is terrible for you, but it certainly does cause hangover effects (and of course, this will vary by person).
    - berberous 13y ago
      It definitely varies by person. I know people who say they consistently get an afterglow and feel even better the next day, whereas others consistently feel the serotonin deficiency and can feel a bit depressed. The jaw clenching seems to be more universal.
      - thatswrong0 13y ago
        There are also supplements that help prevent the negative side effects plus protect against some of the toxicity.. magnesium + gum for the jaw clenching, Vitamin C [1][2] + ALA [3] + Vitamin E [4] + others for antioxidants and preventing neurotoxicity and hepatoxicity. 1: http://www.ncbi.nlm.nih.gov/pubmed/15212815 http://www.ncbi.nlm.nih.gov/pubmed/15212815 2: http://onlinelibrary.wiley.com/doi/10.1002/1098-2396%28200104%2940:1%3C55::AID-SYN1026%3E3.0.CO;2-O/abstract http://onlinelibrary.wiley.com/doi/10.1002/1098-2396%2820010... 3: http://www.ncbi.nlm.nih.gov/pubmed/10619665 http://www.ncbi.nlm.nih.gov/pubmed/10619665 4: http://www.ncbi.nlm.nih.gov/pubmed/11931860 http://www.ncbi.nlm.nih.gov/pubmed/11931860
tachyonbeam 13y ago
Careful. MDMA can have beneficial effects, but there's mounting evidence that it's some degree of neurotoxic. If you use it weekly, you'll likely cause some amount of permanent damage in the long run. I can also tell you that MDMA can cause anxious/depressive episodes that last a few days after use. There's even a name for this (suicide Tuesday). Not everyone experiences this side-effect, but like any other drug, it's not for everyone, and people should be careful with it. It nearly depletes your brain's serotonin reserves, and some people don't deal with that very well at all. A large proportion of users (most?) are not careful: they do not supplement, do not use test kits, do not know how much is in a capsule/pill and will redose multiple times in a night.
- cnp 13y ago
  I agree with this completely. Like everything, moderation is absolutely key. But that being said, unlike many drugs MDMA has a built-in cut-off switch (another perk) which basically prevents you from feeling anything more after about three doses. That's not saying that eager people wont continue to do more (especially if they're on other drugs or at a festival and not thinking clearly) but the effect is basically nil once you get into the 300mg range.
- sppooo 13y ago
  I used a lot of MDMA 20+ years ago. I was immediately aware, on trying it, that it was neurotoxic. I don't know how I knew that, but I did. However, after I quit I saw no evidence of permanent damage. As a fairly high-level software developer, I'm pretty sensitive to the state of my brain, and I don't recall ever experiencing difficulty working more than 2 or 3 weeks after taking MDMA. Also, I only heard about this right before I quit, but a lot of the toxicity can be averted by taking 20mg of fluoxetine 3 to 4 hours into the experience. (It diminishes the drug effect, so you don't want to take it too soon.) The theory I heard is that MDMA or, more likely, one of its metabolites, binds to serotonin receptors and damages them. Taking something else that binds to the receptors, then, can help protect them. I tried it once and it seemed to help. St. John's Wort might work too, and is easier to get. All that said -- I agree that people should be more careful with it. It's a potent psychoactive drug that's harder on the body than most of them, dehydration being a real risk.

by cnp 13y ago

kittycow 13y ago

agreed. I take one whenever i go to a job interview. Without it I'm a stuttering idiot during an interview. where as with ecstasy I turn in to the dos equis beer guy.

thathonkey 13y ago
you probably feel like dos equis beer guy but to the interviewer you just have pupils the size of saucers and can't stop feeling the fabric of your clothes really earnestly
CocaKoala 13y ago
How often to you go to job interviews? If you have lots of them and take MDMA before each one, I think it might not be as helpful as you feel it is.
- kittycow 13y ago
  good point!

WarDekar 13y ago

No hangover? Except for, let's see, a short list: Severely depleted serotonin levels, causing irritability and possibly depression Loss of focus, concentration, and attention (good luck programming competently the day after) Bruxism (jaw clenching/grinding)

cnp 13y ago
Hangovers tend to occur when you've had MDMA mixed with one of the ever-more-frequent mixers such as methamphetamine, cocaine or even MDA, which actually targets dopamine receptors far more prominently than the serotonin and knock you out for days. Pressed pills are usually the culprit, and I would avoid them unless you know exactly where they're coming from. From a wide array of experience, pure MDMA (in recommended doses, meaning 200mg or less) produces less of a hangover than two beers, with a very real "afterglow" which lasts for days after. Excellent focus and concentration included. This is a good read: http://www.cbc.ca/news/canada/british-columbia/pure-ecstasy-can-be-safe-for-adults-health-official-says-1.1229517 http://www.cbc.ca/news/canada/british-columbia/pure-ecstasy-...
- WarDekar 13y ago
  From your own article: "The drug's letdown can include feelings of confusion, irritability, anxiety, paranoia and depression, and people may experience memory loss or sleep problems, jaundice or liver damage." And: "Dr. John Halpern, a Harvard Medical School assistant professor who led the research, said pure MDMA can change core body temperature, heart rate and blood pressure in the short-term, and decrease immune resistance for a few days." Sounds like a hangover to me: "2a : disagreeable physical effects following heavy consumption of alcohol or the use of drugs" http://www.merriam-webster.com/dictionary/hangover http://www.merriam-webster.com/dictionary/hangover I'm not saying MDMA is terrible for you, but it certainly does cause hangover effects (and of course, this will vary by person).
  - berberous 13y ago
    It definitely varies by person. I know people who say they consistently get an afterglow and feel even better the next day, whereas others consistently feel the serotonin deficiency and can feel a bit depressed. The jaw clenching seems to be more universal.
    - thatswrong0 13y ago
      There are also supplements that help prevent the negative side effects plus protect against some of the toxicity.. magnesium + gum for the jaw clenching, Vitamin C [1][2] + ALA [3] + Vitamin E [4] + others for antioxidants and preventing neurotoxicity and hepatoxicity. 1: http://www.ncbi.nlm.nih.gov/pubmed/15212815 http://www.ncbi.nlm.nih.gov/pubmed/15212815 2: http://onlinelibrary.wiley.com/doi/10.1002/1098-2396%28200104%2940:1%3C55::AID-SYN1026%3E3.0.CO;2-O/abstract http://onlinelibrary.wiley.com/doi/10.1002/1098-2396%2820010... 3: http://www.ncbi.nlm.nih.gov/pubmed/10619665 http://www.ncbi.nlm.nih.gov/pubmed/10619665 4: http://www.ncbi.nlm.nih.gov/pubmed/11931860 http://www.ncbi.nlm.nih.gov/pubmed/11931860

tachyonbeam 13y ago

Careful. MDMA can have beneficial effects, but there's mounting evidence that it's some degree of neurotoxic. If you use it weekly, you'll likely cause some amount of permanent damage in the long run. I can also tell you that MDMA can cause anxious/depressive episodes that last a few days after use. There's even a name for this (suicide Tuesday). Not everyone experiences this side-effect, but like any other drug, it's not for everyone, and people should be careful with it. It nearly depletes your brain's serotonin reserves, and some people don't deal with that very well at all. A large proportion of users (most?) are not careful: they do not supplement, do not use test kits, do not know how much is in a capsule/pill and will redose multiple times in a night.

cnp 13y ago
I agree with this completely. Like everything, moderation is absolutely key. But that being said, unlike many drugs MDMA has a built-in cut-off switch (another perk) which basically prevents you from feeling anything more after about three doses. That's not saying that eager people wont continue to do more (especially if they're on other drugs or at a festival and not thinking clearly) but the effect is basically nil once you get into the 300mg range.
sppooo 13y ago
I used a lot of MDMA 20+ years ago. I was immediately aware, on trying it, that it was neurotoxic. I don't know how I knew that, but I did. However, after I quit I saw no evidence of permanent damage. As a fairly high-level software developer, I'm pretty sensitive to the state of my brain, and I don't recall ever experiencing difficulty working more than 2 or 3 weeks after taking MDMA. Also, I only heard about this right before I quit, but a lot of the toxicity can be averted by taking 20mg of fluoxetine 3 to 4 hours into the experience. (It diminishes the drug effect, so you don't want to take it too soon.) The theory I heard is that MDMA or, more likely, one of its metabolites, binds to serotonin receptors and damages them. Taking something else that binds to the receptors, then, can help protect them. I tried it once and it seemed to help. St. John's Wort might work too, and is easier to get. All that said -- I agree that people should be more careful with it. It's a potent psychoactive drug that's harder on the body than most of them, dehydration being a real risk.