If you're intending to have a reasonably-sized stable of clients then there are significant tax and liability advantages to doing things through your own Limite

If you're intending to have a reasonably-sized stable of clients then there are significant tax and liability advantages to doing things through your own Limited Company, but that really is a nomadic existence, you can't just work for one client without risking falling foul of IR35. What do you care about most? Doing something fun, feeling that your efforts are worthwhile to humanity, making money? Everything is a balance of risk and reward, and everyone's motivations tend to be slightly different.