3 ms·what is SF an acronym for? Science Fiction, San Francisco ?by paddy_m 17y agowhat is SF an acronym for? Science Fiction, San Francisco ?philwelch 17y agoScience Fiction. Though a San Francisco convention is a surprisingly interesting idea. Where would you hold it? Oh, right...psawaya 17y agoWell, he said it would be "regional", so I guess it could just as easily be in New Jersey.