You are not doing cancer research, you are not saving lives as a doctor, you are not building hospitals in Africa. If you want to make a meaningful impact on t

You are not doing cancer research, you are not saving lives as a doctor, you are not building hospitals in Africa. If you want to make a meaningful impact on the world, quit your job as a full-stack engineer and go do something more hands-on. Retain your skills and interest in this area on your 'downtime'. Then come back, hungrier than ever, more humble and more experienced of the world than ever. Life doesn't happen in front of a computer screen, it doesn't happen in printed books or on discussion threads. I did something similar to you. But before I did the change I was burnt out and very depressed (I was at an extremely low point of my life). I don't regret it. Believe me. Do some creative destruction. And come back in two-three years time.