The only real pitfall re Bootstrap in my opinion is that Bootstrap sites (especially Bootstrap 2) tend to look, well, bootstrap-y if you don't customize things.

The only real pitfall re Bootstrap in my opinion is that Bootstrap sites (especially Bootstrap 2) tend to look, well, bootstrap-y if you don't customize things. If you want to pay a few bucks instead of customizing things yourself, check out Wrapbootstrap and/or Bootswatch.