Agreed, with a solid regime there will be an initial cost (DOMS and fatigue) but that only lasts for a week or so, then the benefits start to rack up very soon

Agreed, with a solid regime there will be an initial cost (DOMS and fatigue) but that only lasts for a week or so, then the benefits start to rack up very soon after. The best part is the order- the very first thing you earn is feeling better, which is the most important benefit to me! FWIW, I'm on the "stronglifts" program, plus chunks of 30-min medium-high intensity cardio where I can fit it.