You probably can run, but it will take a long slow process. Can you walk a mile? If so, do that several times a week. Gradually increase to two miles. Then jog

You probably can run, but it will take a long slow process. Can you walk a mile? If so, do that several times a week. Gradually increase to two miles. Then jog (very very very slow run) for a a few yards at a time during the walk. Gradually increase the run distance. 6 months to 2 years later, you'll be able to run that whole two miles. A huge barrier to fitness is that it is typically taught and promoted by those who find it easy, and they really can't understand how difficult it is. However, if you persist over a long period of time you can get enormous benefits. And this gradual approach means it is not painful - in fact the slogan ought to be 'no pain maximizes gain'.