One tricky bit is that I think a good solution medium-term will need to handle both media. Right now, a typical academic paper's print format transfers relative

One tricky bit is that I think a good solution medium-term will need to handle both media. Right now, a typical academic paper's print format transfers relatively poorly to the web. But the reading experience you get when you print out a web-formatted document to paper is also typically pretty poor, especially with things like figure layout. It's possible e-readers will someday obsolete print entirely, but I personally still find it difficult to read longer-form stuff on a screen, so I'd like to see better options for print layout of web documents. Technologically these are possible, e.g. PrinceXML shows quite a bit of print-layout stuff you can do with the web-technology stack (though it's unfortunately proprietary), but the bits and pieces don't quite plug together well yet.