Great comments! We expect the beneficial targets to be HLA restricted. We need to do more work to understand if any one individual needs to hit two targets -

Great comments! We expect the beneficial targets to be HLA restricted. We need to do more work to understand if any one individual needs to hit two targets - we think right now that a "master vaccine" would need to contain multiple peptides to cover multiple HLA type individuals yielding at least one "valid" target per individual.