The founder of Asana gave a great talk on that subject for Stanford's Entrepreneurial Thought Leaders (available online if you search). If I remember correctly

The founder of Asana gave a great talk on that subject for Stanford's Entrepreneurial Thought Leaders (available online if you search). If I remember correctly for him changing the world was making it easier for others to do their thing more effeciently. One example he gave was cancer researchers that use Asana which gives them more time for research due to easier project management.