The issue is one of serial vs parallel processing. You cannot treat all hours as equal when you or someone else is the bottleneck for your entire startup/projec

The issue is one of serial vs parallel processing. You cannot treat all hours as equal when you or someone else is the bottleneck for your entire startup/project. In this case the local and the global optimization problem need to be solved together, or it just won't work. That being said, I think that not all local optimization problems are of this type, but some certainly are. And many of the nasty ones fall on founders and startups disporportionately.