Not a bad point, especially given that the current consensus seems to be that the agricultural revolution[1] was a net negative for most individuals in society

Not a bad point, especially given that the current consensus seems to be that the agricultural revolution[1] was a net negative for most individuals in society (evidence of significant wear on the body from bending all day, evidence of worse nutrition), but it was a winning adaptation at the group level. Underscores the point that progress can make us less happy. That said, I strongly believe that we can do anti-aging right and improve the lot of humanity. [1] We only started needing a designated place to poop because we stayed around in one place and became numerous.