This is a very good point. It is important for non-researchers to know that when you want to do a mouse (or rat, dog, or non-human primate) study, you have to

This is a very good point. It is important for non-researchers to know that when you want to do a mouse (or rat, dog, or non-human primate) study, you have to decide what particular strain of mouse to buy. There are MANY options from Harlan, Charles River, etc, and each strain has its own genetic composition. Some of the strains are intentionally inbred, or intentionally outbred. I think this variation might also be more important than some people are giving credit for. It is entirely possible to run a mouse study twice, confirming the results. Then, you can run the same protocol in a different strain and get no results or different results. Then, you have to try to understand which strain might be more applicable in a human population.