There really need to be more studies on the effects of nicotine in isolation from all the other chemicals in cigarettes. There have been studies that have shown

There really need to be more studies on the effects of nicotine in isolation from all the other chemicals in cigarettes. There have been studies that have shown that the MAOIs in tobacco interact with nicotine pretty strongly in creating addiction. I wouldn't be surprised if the MAOIs are also related to why people with mental and mood disorders often self-regulate with tobacco.