5 ms·

Well this sucks. I was going to pay for the test this weekend. Anyone have any idea how useful the health data is without the 23andme interpretation? I'm guess

Well this sucks. I was going to pay for the test this weekend. Anyone have any idea how useful the health data is without the 23andme interpretation? I'm guessing it will be basically useless.

kingkawn 13y ago
Their interpretations were based on poorly proven associations between genes and disease-outcomes. I bet with the info you could look up on wikipedia/google scholar much of what you needed to know. But it depends on the format of this data dump.
- Afforess 13y ago
  No, that is pure FUD. 23andme provides a confidence assessment for the associations and risks. Here is a screenshot from their site: https://dl.dropboxusercontent.com/u/49805/confidence.png https://dl.dropboxusercontent.com/u/49805/confidence.png
  - infocollector 13y ago
    And no one has problems with their privacy policy?
    - Afforess 13y ago
      Your DNA is pretty much public domain anyway. You drop tons of it all over the place.
      - infocollector 13y ago
        Thankfully I do not label it with my name ;)
  - kingkawn 13y ago
    All well and good that intervals of confidence exist in medical research. But good understandings of these associations have been reached with very few genes. The categories alone do not prove that they apply broadly enough to justify the product.
GraffitiTim 13y ago
Since they're still going to provide the data to new users, I wonder if some of their interpretations could be recreated and published by existing users who still have access to the interpretations.
- khomenko 13y ago
  Yes, for the mendelian ones that can be inferred in a relatively straightforward way from the raw data. Not really, for the more complicated risk assessments.
sanxiyn 13y ago
You can get the basically same report running Promethease on 23andMe data dump. There is a website even providing automatic 23andMe data import using 23andMe's API.
- midas007 13y ago
  Get SNPs via https://www.23andme.com/you/download/ https://www.23andme.com/you/download/ and then process with http://www.snpedia.com/index.php/Promethease http://www.snpedia.com/index.php/Promethease
khomenko 13y ago
You can run the raw data through a 3rd party tool like Promethease (http://snpedia.com/index.php/Promethease http://snpedia.com/index.php/Promethease) while you wait for the FDA kerfuffle to work itself out. YMMV though.

Well this sucks. I was going to pay for the test this weekend. Anyone have any idea how useful the health data is without the 23andme interpretation? I'm guessing it will be basically useless.

kingkawn 13y ago

Their interpretations were based on poorly proven associations between genes and disease-outcomes. I bet with the info you could look up on wikipedia/google scholar much of what you needed to know. But it depends on the format of this data dump.

Afforess 13y ago
No, that is pure FUD. 23andme provides a confidence assessment for the associations and risks. Here is a screenshot from their site: https://dl.dropboxusercontent.com/u/49805/confidence.png https://dl.dropboxusercontent.com/u/49805/confidence.png
- infocollector 13y ago
  And no one has problems with their privacy policy?
  - Afforess 13y ago
    Your DNA is pretty much public domain anyway. You drop tons of it all over the place.
    - infocollector 13y ago
      Thankfully I do not label it with my name ;)
- kingkawn 13y ago
  All well and good that intervals of confidence exist in medical research. But good understandings of these associations have been reached with very few genes. The categories alone do not prove that they apply broadly enough to justify the product.

GraffitiTim 13y ago

Since they're still going to provide the data to new users, I wonder if some of their interpretations could be recreated and published by existing users who still have access to the interpretations.

khomenko 13y ago
Yes, for the mendelian ones that can be inferred in a relatively straightforward way from the raw data. Not really, for the more complicated risk assessments.

sanxiyn 13y ago

You can get the basically same report running Promethease on 23andMe data dump. There is a website even providing automatic 23andMe data import using 23andMe's API.

midas007 13y ago
Get SNPs via https://www.23andme.com/you/download/ https://www.23andme.com/you/download/ and then process with http://www.snpedia.com/index.php/Promethease http://www.snpedia.com/index.php/Promethease

khomenko 13y ago

You can run the raw data through a 3rd party tool like Promethease (http://snpedia.com/index.php/Promethease http://snpedia.com/index.php/Promethease) while you wait for the FDA kerfuffle to work itself out. YMMV though.