> Oh you need that abandoned Chemistry application from 2006 that depends on X11? Spin up a VM. No, just load a compatibility library, possibly in the form of

> Oh you need that abandoned Chemistry application from 2006 that depends on X11? Spin up a VM. No, just load a compatibility library, possibly in the form of a wrapper program. If Wine can run Windows programs on Linux by translating Win32 to POSIX and X11, which it can to a very usable extent, something equivalent can translate X11 library calls to whatever the new library speaks, especially since it will be able to use whatever X11 code it needs.