I use Remember the Milk, and over the last 10 months it has become ingrained into my workflow. I actually cite RTM's $25 a year freemium model as a good example

I use Remember the Milk, and over the last 10 months it has become ingrained into my workflow. I actually cite RTM's $25 a year freemium model as a good example of a startup not using ads to fund themselves. I gladly pay $25 a year for it because it helps me organize so well. Slate put it in 2nd because they didn't seem to need all the features. For me the iPhone interface is all I need to pick it as #1.