I think that using the term "in principle" is the only way to pretend this question is difficult to answer. We observe what appears to be inherent unpredictabil

I think that using the term "in principle" is the only way to pretend this question is difficult to answer. We observe what appears to be inherent unpredictability at the quantum level. The butterfly effect claims that imperceptible differences in starting conditions can cause significant effects (over time.) If this is an accurate model of how our universe works, we would expect that not only is nothing deterministic, but it would be extremely difficult to predict the state of reality over even short time periods. This is exactly what we observe on the macroscopic level.