The biggest aspect of Fantasy Football is the draft - where you select your players before the start of the season. So the area where you could apply some actua

The biggest aspect of Fantasy Football is the draft - where you select your players before the start of the season. So the area where you could apply some actual hacking is the projection/simulation of player performance to come up with your own rankings. Hopefully, this could allow you to pick undervalued players - so similar to predicting stocks. Basically you can treat it as a statistical modeling exercise and go from there. There is no realtime aspect to fantasy sports, you are usually setting a roster weekly, waiting for the games to be played for the week, and then seeing the results. So something like high frequency trading doesn't really apply.