>Functionally, it makes little to no difference whether you're writing something that compiles down to JS or writing something that compiles down to its own run

>Functionally, it makes little to no difference whether you're writing something that compiles down to JS or writing something that compiles down to its own runtime (assuming you turn source maps on your browser). It actually makes a big difference. You can't use profiles, debugger, libraries, and other stuff which is platform specific but have to use JavaScript ones. Often, they don't play well with with languages which generate to JS.