3 ms·
What about Linezolid? http://en.wikipedia.org/wiki/Linezolid http://en.wikipedia.org/wiki/Linezolid
by eranation 13y ago
What about Linezolid? http://en.wikipedia.org/wiki/Linezolid http://en.wikipedia.org/wiki/Linezolid
- w4 13y agoThe Wiki article you linked specifically mentions Linezolid isn't necessarily effective against many Gram-negatives (the resistant bacteria): Linezolid has no clinically significant effect on most Gram-negative bacteria. Pseudomonas and the Enterobacteriaceae, for instance, are not susceptible.[90] In vitro, it is active against Pasteurella multocida,[2][91] Fusobacterium, Moraxella catarrhalis, Legionella, Bordetella, and Elizabethkingia meningoseptica, and moderately active (having a minimum inhibitory concentration for 90% of strains of 8 mg/L) against Haemophilus influenzae.[87][90] It has also been used to great effect as a second-line treatment for Capnocytophaga infections.[43][92]
- eranation 13y agoOh, thanks, missed that.
- carbocation 13y agoYou basically have polymixins (colistin) and, depending on resistance profile, fosfomycin and tigecycline. Colistin is avoided if possible because of nephrotoxicity, but as usual, medicine is a field heavily involved in balancing risks and benefits.
- eranation 13y agoI wish I haven't skipped Biology in school...