If you are interested in high accuracy for highly diverged DNA, take a look at: http://www.ncbi.nlm.nih.gov/pubmed/20733242 http://www.ncbi.nlm.nih.gov/pubmed/

If you are interested in high accuracy for highly diverged DNA, take a look at: http://www.ncbi.nlm.nih.gov/pubmed/20733242 http://www.ncbi.nlm.nih.gov/pubmed/20733242 https://github.com/akhudek/feast https://github.com/akhudek/feast Sadly, I haven't seen this research be applied anywhere. I'm not sure if it's a lack of advertising, or that there is nothing interesting at extreme divergences.