what about feedback effect and pineal gland attrofiation? every hormone that you have in excess of what the body expects, have compensation of the opposing mes

what about feedback effect and pineal gland attrofiation? every hormone that you have in excess of what the body expects, have compensation of the opposing message hormone, feedback effect. anyone has any idea which one is for this case? another consequence is that the original producer of such hormone will get de prioritized by the body and atrophies after too much time. does this happen here?