Many of the ones near the end are from Gurren Lagann, a show that follows a guy through his life as he overcomes an ever-larger series of problems, with "larger

Many of the ones near the end are from Gurren Lagann, a show that follows a guy through his life as he overcomes an ever-larger series of problems, with "larger" having a very literal representation -- from childish bullies, to the head of the village, eventually up to all of existence :P (Or something like that; my memory is terrible and I've not watched it for years)