You can do a couple pieces of day, with no problem, IME. Chew it up well and let it sit in your lip for optimal absorption. That said, when nicotine is exposed

You can do a couple pieces of day, with no problem, IME. Chew it up well and let it sit in your lip for optimal absorption. That said, when nicotine is exposed to oral tissues, it may be promoting: -oral cancer Source: http://www.ncbi.nlm.nih.gov/pubmed/20338106 http://www.ncbi.nlm.nih.gov/pubmed/20338106 -gingivitis Source: http://www.ncbi.nlm.nih.gov/pubmed/20337880 http://www.ncbi.nlm.nih.gov/pubmed/20337880 -receding gums Source: don't have a specific study handy, but this high-level review mentions it, and other issues: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2933534/ http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2933534/ Keep in mind, these are all slight chances. If you do this regularly for years, it may be of concern. Every once in a while? No biggie. Patch will get you around all of these, specific issues at least. There's still that whole 'carcinogenic, overall' thing.