I think you might have evaded the question :-). There really are some "webapps" with tight performance requirements. For example, Google's web frontend is a st

I think you might have evaded the question :-). There really are some "webapps" with tight performance requirements. For example, Google's web frontend is a statically compiled C++ application. And yes, anithero, you could write that sort of thing in Cython and with some type declarations get acceptable native performance. You will probably miss a few opportunities for optimization but catch the low-hanging fruit and get an orders of magnitude speedup over Python.