When you say things like "realizing how large the universe is", "how meaningless life is", do you really mean that your mental state is impacted by the answers

When you say things like "realizing how large the universe is", "how meaningless life is", do you really mean that your mental state is impacted by the answers to these questions/implications of these realisations? How does it affect you? I ask because while the ideas are interesting to me, they have always seemed fairly irrelevant. Sure, the universe is huge, but I don't think knowing that is going to change me. The way I see it, it has no impact on the way I live my life and I can't see anything I do having an impact on that. I mean the questions genuinely, I realise that not everyone sees things the same way.