There are many studies. Here's one: http://jama.jamanetwork.com/article.aspx?articleid=185157 http://jama.jamanetwork.com/article.aspx?articleid=185157 This s

There are many studies. Here's one: http://jama.jamanetwork.com/article.aspx?articleid=185157 http://jama.jamanetwork.com/article.aspx?articleid=185157 This study found that SSRIs provided little to no benefit over placebo for patients suffering from mild to moderate depression. SSRIs did provide a benefit to patients suffering from severe depression. This raises the question, how many of the 30+ million Americans currently prescribed anti-depressants actually suffer from severe depression and benefit from the drugs? How many are taking it unnecessarily, subjecting themselves to unintended side effects and eventual withdrawal symptoms.