Being downvoted for not enough citations, I guess: For the energy load incurred by adding to the gene sequence: http://www.sciencedirect.com/science/article/p

Being downvoted for not enough citations, I guess: For the energy load incurred by adding to the gene sequence: http://www.sciencedirect.com/science/article/pii/073497509500004A http://www.sciencedirect.com/science/article/pii/07349750950... Brittleness of genes: http://en.wikipedia.org/wiki/Genetic_diversity http://en.wikipedia.org/wiki/Genetic_diversity Potato famine in general.