The linked page provides this: "Batch processing Available from command line. ImageAlpha is based on pngquant. You'll find compiled pngquant executable in Imag

The linked page provides this: "Batch processing Available from command line. ImageAlpha is based on pngquant. You'll find compiled pngquant executable in ImageAlpha.app/Contents/Resources directory." So you should be able to script that. Also for people on non-Mac systems, it appears this is available for Linux / Windows as well: https://github.com/pornel/pngquant https://github.com/pornel/pngquant Edit: Better link to pngquant: http://pngquant.org/ http://pngquant.org/