I think it wouldn't. I believe your lungs in a vacuum will de-oxygenate your blood regardless, so you only have as much time as it takes for that blood to hit

I think it wouldn't. I believe your lungs in a vacuum will de-oxygenate your blood regardless, so you only have as much time as it takes for that blood to hit your brain. Hyperventilating is good for removing CO2 from your blood, which reduces your "I really need to breath" reflex (turns out that is, at least largely, cause by the presence of CO2 rather than the absence of O2). From personal experience I can tell you this can allow you to push yourself further without breathing, but you also run the risk of blacking out because you pushed too far (I don't have experience with that part).