Well, it's one more thing to worry about. Consider someone dropping their day job to work full time on their newly created startup. Every bit helps to save cost

Well, it's one more thing to worry about. Consider someone dropping their day job to work full time on their newly created startup. Every bit helps to save costs, which means less stress and a more enjoyable adventure. However, are these affordable cities "at the end of the world"? I mean, incomunicated and such. I'm not American, so I can't really tell from checking the list. In that case it might end up being a burden if you don't like travelling. But looking positively again, it could be a good opportunity to start small groups of hackers in places where there aren't any and help each other out :)