It's extremely dependent on the niche you're serving. Something like a games website will, at best, get around $3 CPM (counting all ad blocks). By contrast, so

It's extremely dependent on the niche you're serving. Something like a games website will, at best, get around $3 CPM (counting all ad blocks). By contrast, something about cancer or payday loans will probably get $20 CPM or more. This is further complicated by how you're doing ads, but let's just assume that you're planning to go the Adsense/similar route. (If you were thinking to run your own ads and optimise them yourself, you can make significantly more than the CPMs above, but there's more work and specialised knowledge involved.) It's perfectly possible to make a very nice income off 50k visits a month, but you have to be in a very competitive niche. As a rough guideline (and, as you may have guessed, I have recent practical experience in this area), aim for 800,000 visitors a month in a low-CPM niche, or 100,000 a month in a high-CPM one.