What do you mean "modulate insulin?" Insulin is produced in response to elevated blood sugar. Modulating it would, presumably, leave you with high blood sugar

What do you mean "modulate insulin?" Insulin is produced in response to elevated blood sugar. Modulating it would, presumably, leave you with high blood sugar, all other things being equal. Diabetes mellitus is the syndrome of high blood sugar. If you want to become diabetic, take some streptozotocin :)