Not every drug causes a rebound effect. Manipulating neurotransmitters directly, our most common method of psychoactivity in mood-altering substances, almost al

Not every drug causes a rebound effect. Manipulating neurotransmitters directly, our most common method of psychoactivity in mood-altering substances, almost always leads to rebound. However, there are many ways of affecting receptors further up the metabolic chain. For example, recent research has focused on neurohormones are alternatives to benzodiazepines for anxiety treatment. Some of these may be, in theory, less addictive or entirely non-addictive. Unfortunately, the current drugs are very effective for short duration courses, the most common medical use. A less restricted market would incentive drug companies to find less harmful substances for recreational use. In a regulated market, you could even use the tax burden to further shape the public's preferences.