if you run antivirus software, how do you know you're not infected? many malwares now will partially paralyze your antivirus so that it seems all is well, but y

if you run antivirus software, how do you know you're not infected? many malwares now will partially paralyze your antivirus so that it seems all is well, but your computer is operated by someone else. TDSS would do this as long ago as 2008...