You don't have to be interested in everything they say. Twitter is asynchronous. These are people who may say something potentially interesting when you are onl

You don't have to be interested in everything they say. Twitter is asynchronous. These are people who may say something potentially interesting when you are online, and you may answer at that point. One way to see it is that you are creating your own irc channel with 500 people that you choose. There may be reasons to be interested in everything 500 people say. They could be your employees and you want to make sure you record everything they tweet. They could be your customers. There are many use cases out there that we can't think of.