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The Fat/Cholesterol diet to Heart Disease explanation has always been based on correlation and the work to find an physiological mechanism has always been weak.
by zmanian 13y ago
The Fat/Cholesterol diet to Heart Disease explanation has always been based on correlation and the work to find an physiological mechanism has always been weak.
It is still early days on the gut bacteria/TMAO hypothesis but it does fit with my knowledge of the relevant biology. http://www.nytimes.com/2013/04/08/health/study-points-to-new-culprit-in-heart-disease.html?pagewanted=all http://www.nytimes.com/2013/04/08/health/study-points-to-new...
The arguments that fructose is toxic to the liver also seem compelling. I try to classify sugar in the same category as alchohol in my diet.
- stephengillie 13y agoApples and oranges are toxic to the liver? I don't buy it.
- rosser 13y agoApples and oranges aren't toxic to the liver, fructose is. [1][2][3] When found in fruit, fructose is bound up tightly with fiber, which drastically slows the rate at which it is absorbed and metabolized. Unbound, in fructose-sweetened products, it pretty much slams into your liver, which is then forced to deal with the onslaught. [1] Fructose Consumption as a Risk Factor for Non-alcoholic Fatty Liver Disease: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2423467/ http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2423467/ [2] Abundance of fructose not good for the liver, heart: http://www.health.harvard.edu/newsletters/Harvard_Heart_Letter/2011/September/abundance-of-fructose-not-good-for-the-liver-heart http://www.health.harvard.edu/newsletters/Harvard_Heart_Lett... [3] High Fructose Corn Syrup Linked to Liver Scarring, Research Suggests: http://www.sciencedaily.com/releases/2010/03/100322204628.htm http://www.sciencedaily.com/releases/2010/03/100322204628.ht...