This design-in-markup concept has been around for a while (I like the new term "NoPSD" though). I tend to flip both ways on this issue. For expediency's sake, a

This design-in-markup concept has been around for a while (I like the new term "NoPSD" though). I tend to flip both ways on this issue. For expediency's sake, and often in terms of usability and performance, designing in CSS definitely wins out. The problem is that you end up with bland designs that tend to conform to the whims of the technology rather than the type of creative elegance that a PSD affords. Because photoshop is removed from the tech, a designer in Photoshop can use their imagination a little bit and force pushing the boundaries of the technology in ways that a developer typically wouldn't. Even when you are a developer and aware of the tech, spinning the design in Photoshop (and even better, further abstracted down to pencil sketches etc) just always gives more creative and aesthetically pleasing results in my opinion.