Those who are affected by LSD in that way will probably also be more susceptible to drug induced HPPD or Schizophernia from other controlled and non-controlled

Those who are affected by LSD in that way will probably also be more susceptible to drug induced HPPD or Schizophernia from other controlled and non-controlled substances. It has to do with the structure of the brain. http://bjp.rcpsych.org/content/178/4/337.full http://bjp.rcpsych.org/content/178/4/337.full Basically they are born with less ability to distinguish reality from fiction. A good indication for this would be the well known ink spot test. Responsible self-admission of controlled substances would always advocate starting at the dose that might cause an adverse allergic reaction of some sort, and move up from there. I've seen a Scanner Darkly, and I've tried hard drugs. In my experience and knowledge of stimulating drugs like amphetamines and esp. cocaine. The chance of psychosis from these line of drugs and the potential of abuse are of an order of magnitude worse, while we blindly prescribe our ADD and ADHD suffering kids to methylphenidate (Ritalin) and amphetamine salts (Adderall). I would advice you to look them up. The abuse potential for these kind of drugs are huge with ADD/ADHD patients since their disorder pretty much means they require more dopamine stimulation to be able to complete tasks, and these drugs are very much addictive in nature because of their actions on the dopamine system. Stimulating this area in the brain is way more "rewarding" than for example serotonergic drugs like LSD. I understand that a lot of street drugs are adulterated or chemically inferior to the medical grade stuff, but it is still hypocritical and dangerous to make a Black/White area of what is supposedly not bad for you (i.e. prescriptions, OTC or legal substances ) and bad for you (controlled substances). I understand that these drugs are prescribed under doctors supervision, but the reality learns that this is usually not a game stopper for abusers. Also they are being given to patients for a number of disorders without adequate research backing their perceived safety profile. Long-term effects on kids and teenagers who have been on these medications are not known at all.