Both gunicorn and uwsgi are good stuff. Though a new contender is Phusion Passenger (https://www.phusionpassenger.com/ https://www.phusionpassenger.com/), origi

Both gunicorn and uwsgi are good stuff. Though a new contender is Phusion Passenger (https://www.phusionpassenger.com/ https://www.phusionpassenger.com/), originally designed for Ruby but recently gained official support for Python. With the next release (4.0.6), Python support will be raised from beta status to production-ready status. Like uwsgi, it performs the bulk of the process management for you. It goes a step further than uwsgi by integrating directly into Nginx, so that the web server is the only thing you have to deal with.