The question is not so much "where is NUMA effective," but, "given that for highest speeds memory needs to be attached directly to the CPU, how do we deal effec

The question is not so much "where is NUMA effective," but, "given that for highest speeds memory needs to be attached directly to the CPU, how do we deal effectively with the case of multiple CPUs?" If you want multi-socket SMP, these days you need to deal with its inherent NUMA architecture. Or sweep it under the rug as Apple did with the old Mac Pro and sacrifice performance.