This was a fun read but we've already reached the meta-discussion of the meaningfulness of entrepreneurs so it's probably time to move on. The reality is that

This was a fun read but we've already reached the meta-discussion of the meaningfulness of entrepreneurs so it's probably time to move on. The reality is that entrepreneurs cannot solve the Big Problems or big problems - the investment and time horizon of these problems means that traditional structures, e.g. large companies, research organizations and governments have to step in. Disruption is for the easy stuff, hard stuff still has to be solved the slow way, with decades of hard work.