...opportunities for start-ups to exploit to gain a foothold against the likes of DropBox, Google Drive, SkyDrive, ect... One could almost read your wording to

...opportunities for start-ups to exploit to gain a foothold against the likes of DropBox, Google Drive, SkyDrive, ect... One could almost read your wording to have said, "...opportunities for start-ups to do something that the likes of DropBox, Google Drive, SkyDrive, ect wouldn't allow you do and likely won't ever allow you to do." The problems of going against these behemoths is that no company will trust you over them, which means you'll have to fight for B2C. Which is fine, except that Google and the others are marketing the crap out of that to their email customers all day long. That's the 'wrong row to hoe' as they say. So back to the "interpretation" of what you said - the only opportunities that I can see are serving content that the big guys won't touch: porn, piracy, encryption, etc. But that puts you square in the middle of two groups: aggressive law enforcement types and "unethical" groups of others. That's just not a place I'd want to be.