It's an interesting question, both for early stage and more advanced startups. I'd put Huddle in the latter camp; they're the London tech entrepreneurship scene

It's an interesting question, both for early stage and more advanced startups. I'd put Huddle in the latter camp; they're the London tech entrepreneurship scene's darlings, they're kinda the star British startup at the moment, and it really makes sense for them to get more exposure and credibility abroad. On the other hand going to SF puts them right against a ton of baby competitors and of course good old 37s. For those of us starting out, we have the same question and decision to make - try to start abroad and establish credibility, contacts and capital from the start, or build up brick by brick in the UK and then move once we have made our name locally. There is never going to be a right, one-size-fits-all answer. For example, I'm in Edinburgh because that's the best place to be for the tech I'm developing, but it's certainly not the best place to be for the business - so I'll move. Right at the early stages, it's more about cost of living versus opportunities than easy access to millions of VC money anyway. One caveat to note though, as a lawyer I recently spoke to told me: if you incorporate in the US, even if you're British through and through, you're going to have trouble attracting UK money. You're also going to have extra legal fun if you do return to the UK, since most UK lawyers aren't experts in US corporate law so you'll have to hire someone specialist or across the pond. Similarly if you incorporate in the UK and then want to do stuff in the US, you'll run into fun there too. Bottom line is leave off incorporating as long as possible :P