I guess we're disagreeing with what is meant by innovation. For me it means big ideas. Better tires on cars is innovation but it's not satisfying to me. I th

I guess we're disagreeing with what is meant by innovation. For me it means big ideas. Better tires on cars is innovation but it's not satisfying to me. I think Thiel also means big ideas -- hence the 140 character quote. I like your enthusiasm and your list is fantastic. I haven't seen Meredith Patterson's stuff. It looks interesting. But we were also "on the cusp" of curing cancer in the 70's. This is personal, I guess. I've spent an inordinate time on deep research and I've done it on my own. It's frustrating to watch while things like the Kickstarter for T-shirts get drowned in financing while I count pennies. I'll try to be more optimistic but there's nothing wrong with saying, "Let's stop chasing money and start chasing something more. Something bigger. Something better."