Shift+Reload takes care of all caching issues. It's hard to nail down the difference between Chrome Dev Tools and Firebug with just one thing. For me it's not

Shift+Reload takes care of all caching issues. It's hard to nail down the difference between Chrome Dev Tools and Firebug with just one thing. For me it's not one killer feature it's a quality of life issue. It's all the little things that, IMHO, Chrome Dev Tools does right. I have no problem using Firebug or even the Firefox Inspector when needed to actually find a Firefox specific problem but for working day in and day out, I prefer the experience of the Chrome Dev Tools.