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Whole organ decellularization is not new - we've had transparent heart ECMs for quite some time. By loading the brain here with monomers, they kill the organ, w
by solox3 14y ago
Whole organ decellularization is not new - we've had transparent heart ECMs for quite some time. By loading the brain here with monomers, they kill the organ, whereas you can still use the transparent heart if you reload it with cells. Similar thing, different purposes.
- JulianMorrison 14y agoYou kill it, but I have to wonder if you kill the information? it sounds like it could be used to do uploads, transhumanism style.
- swamp40 14y agoThat totally freaks me out...
- RVijay007 14y agoJust to clarify, this is not whole organ decellularization. The brain tissue, with it's neurons, glia, ECM, are left all in tact, along with their proteins, mRNA, etc. Now, instead of having to slice the brain into micrometer slices just to understand architecture at a localized level, you can understand the architecture of the whole brain's network down to the cellular level, as well as do both immunohistochemistry and in-situ hybridization to probe what kind of proteins and molecular markers are present throughout the brain. This is nothing short of a revolution in experimental technique not only for neuroscience, but all of pathology.
- deleted 14y ago[deleted]