3 ms·
Points well taken. While my comment falls short of claiming that dementia is linked to lack of sleep, I was primed by the following research in the media recen
by woodchuck64 14y ago
Points well taken. While my comment falls short of claiming that dementia is linked to lack of sleep, I was primed by the following research in the media recently:
"Sleep duration and all-cause mortality": http://www.ncbi.nlm.nih.gov/pubmed/20469800 http://www.ncbi.nlm.nih.gov/pubmed/20469800
"Disturbances to the sleep-wake cycle predict future diagnoses of Alzheimer’s disease. ": http://www.abstractsonline.com/Plan/ViewAbstract.aspx?sKey=fd313178-35c6-4098-9231-19b31db40132&cKey=6c052583-7bb1-46d4-82db-cc98608e4e30&mKey={70007181-01C9-4DE9-A0A2-EEBFA14CD9F1} http://www.abstractsonline.com/Plan/ViewAbstract.aspx?sKey=f...
The first, a survey, seems to show that too little sleep increases all-cause mortality (i.e. that "aging" you mention), the second suggests that sleep disturbances (unknown, admittedly how that relates to sleep duration) may be linked (cause or effect unknown) with Alzheimer's.
- gwern 14y agoEh. Correlations are notoriously weak, and the causation could just as plausibly be reversed (sleep is, after all, a brain activity); this may just be picking up conditions causing sleep abnormalities, which would explain in your first link why they also found an association with too much sleep as well ("Long duration of sleep was also associated with a greater risk of death").
- woodchuck64 14y agoA 2009 article that hints the causation could be due to sleep, at least in mice: http://www.sciencemag.org/content/326/5955/1005 http://www.sciencemag.org/content/326/5955/1005 (see also http://en.wikipedia.org/wiki/Beta_amyloid#Circadian_rhythm_of_amyloid_beta http://en.wikipedia.org/wiki/Beta_amyloid#Circadian_rhythm_o...).